Face Analysis — Longevity
AI-Based Contactless Longevity & Metabolic Health Platform

Frontal and lateral profile photos + a short voice recording yield an AI-powered, contactless and device-independent assessment of biological age, longevity score, metabolic risk and 18+ parameters.

Developed by Dr. Siyra Seren.
Contactless (Photo + Voice)18+ Metabolic ParametersVoice BiomarkerScreening & Triage
Table of Contents
1What is Longevity Analysis?
2Technology: Vision LLM + Voice Acoustic Biomarker
3Evaluated Parameters
4Voice Biomarker (Acoustic Analysis)
5Clinical Value & Decision Support
6ESG & Sustainability
7Scientific References
Vision
A software-centric digital health platform that produces clinically meaningful longevity and metabolic assessment from standard consumer devices (phone, tablet, PC) — instead of expensive lab tests and invasive sensors.
Use Cases
In-clinic pre-screening, longevity follow-up, at-home self-assessment and tele-health remote monitoring.
1
Section 1

What is Longevity Analysis?

Longevity & Metabolic Assessment — Longevity Analysis (Odiosoft Face Analysis) is an AI-powered, contactless digital health assessment platform that combines frontal and lateral profile photos with a short voice recording to produce biological age, overall longevity score and a metabolic risk profile. While a metabolic and functional profile is derived from the face image, the acoustic properties of voice yield neurological, respiratory and autonomic nervous-system indicators.

Subtle structural and tissue changes in the face (skin hydration, elasticity loss, oxidative stress, periorbital signs, jawline/neck) and lateral-profile anatomical landmarks (cervical angle, hyoid position, retrognathia) are well-documented visual biomarkers of longevity and metabolic health. The system quantifies these signatures through image processing and large language model (LLM) inference.

Core Capabilities

  • 12 frontal + 6 lateral parameters + 5 voice-biomarker metrics = 18+ parameters
  • Biological-age estimate, overall longevity score (0-100) and aging-speed indicator
  • Cardiovascular, diabetes and OSAS risk scores + metabolic-risk classification
  • Device-independent: runs with only a phone/tablet/PC camera and microphone
Clinical Positioning
The system is a screening and decision-support tool; it does not replace a definitive medical diagnosis. AI models can err; results are produced to support a physician's clinical assessment. The final diagnosis and treatment decision belongs to the specialist physician.
2
Section 2

Technology: Vision LLM + Voice Acoustic Biomarker

The platform combines image processing with multimodal large language model inference. Frontal and lateral profile images are sent to a vision-LLM together with the patient's demographic data; the voice recording is processed in real time in the browser to extract acoustic features (F0, jitter, shimmer, HNR) and interpret them clinically.

Workflow

  • Frontal + lateral profile photo upload and short voice recording (5+ s)
  • Images uploaded to secure cloud; vision-LLM evaluates image + demographic data together
  • Voice processed in browser; F0, jitter, shimmer, HNR features extracted
  • Per-parameter 0-100 score, category and clinical commentary produced
  • Longevity score, biological age and risk scores (cardiovascular/diabetes/OSAS) computed

Software-Centric Architecture

Hardware-Independent
No extra sensors, electrodes or blood draw; only camera and microphone.
Web-Based (SaaS)
API-first architecture; integrates with EMR and health platforms.
Multimodal AI
Vision + voice + clinical data interpreted jointly by a multimodal LLM.
Telemedicine-Ready
Results stored digitally; remote consultation and longitudinal tracking.
3
Section 3

Evaluated Parameters

The analysis provides multi-layered parameters across frontal, lateral and voice-biomarker groups. Each parameter is reported as percentage (0-100), description and severity; the overall longevity score and biological-age estimate are weighted derivatives.

Frontal (12)
Skin hydration/elasticity, oxidative stress, cortisol load, thyroid, insulin resistance, inflammation, cardiovascular, neurological, sleep, immune, mitochondrial energy
Lateral (6)
Cervical angle/forward head, jaw position (retrognathia), submental fat, hyoid position, neck skin, nasolabial angle
Voice Biomarker (5)
Neurological (jitter), respiratory (HNR), vocal aging (shimmer), autonomic stress (F0), voice activity
Risk Scores
Cardiovascular, diabetes, OSAS risk scores + metabolic-risk classification
Longevity
Overall longevity score (0-100), biological-age estimate, aging speed

Output Format

  • Per parameter: percentage, description, severity, category
  • Summary: longevity_score, biological_age, aging_speed
  • Cardiovascular/diabetes/OSAS risk scores + metabolic-risk classification
  • Printable full report (PDF) and date-based comparative trend
4
Section 4

Voice Biomarker (Acoustic Analysis)

The voice biomarker module extracts acoustic features — fundamental frequency (F0), jitter (period variability), shimmer (amplitude variability) and HNR (harmonics-to-noise ratio) — from a short voice recording to produce neurological, respiratory and autonomic indicators. These features are well documented in the voice-based health-biomarker literature.

J
Jitter
Period stability — neurological
S
Shimmer
Amplitude stability — vocal aging
H
HNR
Harmonics-to-noise — respiratory
F
F0
Fundamental frequency — autonomic stress
V
Voiced
Voiced-frame ratio — activity

Interpretation & Safety

  • Scores are based on AI acoustic analysis; not a diagnosis
  • Reliability drops for low-quality recordings
  • Clinical commentary supports physician assessment, no prescription
  • Per-patient data isolation (RLS) and KVKK/GDPR compliance
Strategic Value
The voice biomarker complements image-based longevity assessment to provide a multimodal health profile, combining visual + acoustic data in a single session.
5
Section 5

Clinical Value & Decision Support

As a screening and pre-triage tool, the platform supports clinical workflows. The longevity score and metabolic-risk mapping provide the physician with structured, reproducible and comparable data. The final diagnosis and treatment decision always belongs to the specialist physician.

Screening
Community/clinic-based non-invasive longevity and metabolic pre-screening.
Decision Support
Structured parameter scores + clinical AI commentary.
Follow-up
Longitudinal trend: biological age and longevity score tracked over time.

Safety Architecture (Human-in-the-loop)

  • AI output is not a diagnosis; it informs the physician's assessment
  • High-risk metabolic findings warrant specialist consultation
  • AI commentary contains no prescription/treatment recommendation
  • KVKK/GDPR-compliant sensitive-data approach and per-patient data isolation

Integration Scenarios

Tele-Health
Remote consultation, at-home follow-up and mobile-device capture.
Pre-Triage
Rapid identification of high-risk individuals and referral to specialists.
6
Section 6

ESG & Sustainability

The software-centric architecture aligns with EU carbon-reduction and ESG goals. Hardware independence brings medical-consumable use close to zero and reduces the carbon footprint from patients' physical travel through tele-health.

Zero Hardware
No extra sensors/electrodes/blood draw; low carbon footprint.
Zero Consumables
No single-use probes/cannulas/apparatus; near-zero clinical waste.
Digital Logistics
Web-based analysis; removes the need for patient travel to clinic (tele-health).

Roadmap

Phase 1
Clinical deployment of the Face Analysis longevity module.
Phase 2
Deep-learning-based personalized longevity estimation.
Phase 3
Holistic health follow-up and predictive analytics suite.
7
Section 7

Scientific References

The following studies establish the clinical validity of face-based longevity/metabolic biomarkers and voice acoustic biomarkers. Longevity Analysis is inspired by this literature; it is not a replacement for it.

1.Wanigatunga AA, Liu F, Dougherty RJ, Roche KB, Urbanek JK, Zampino M, Simonsick EM, Tian Q, Schrack JA, Ferrucci L. Relationship between skeletal mitochondrial function and digital markers of free-living physical activity in older adults. Geroscience. 2024 Dec;46(6):6173-6182. doi: 10.1007/s11357-024-01212-1. Epub 2024 May 29. PMID: 38809390.
2.Dibeklioglu H, Alnajar F, Ali Salah A, Gevers T. Combining facial dynamics with appearance for age estimation. IEEE Trans Image Process. 2015 Jun;24(6):1928-43. doi: 10.1109/TIP.2015.2412377. Epub 2015 Mar 13. PMID: 25781877.
3.Xu X, et al. Facial aging, cognitive impairment, and dementia risk. Alzheimers Res Ther. 2024 Nov 6;16(1):245. doi: 10.1186/s13195-024-01611-8. PMID: 39506848 PMCID: PMC11539626.
4.Rodriguez-Porcel F, et al.; the Diagnosis and Treatment Working Group, CurePSP Center of Care (CoC) Network. Voice and Speech in Atypical Parkinsonian Disorders. Mov Disord Clin Pract. 2026 Jan 10:10.1002/mdc3.70515. doi: 10.1002/mdc3.70515. PMID: 4151813.
5.Rusz J, Krack P, Tripoliti E. From prodromal stages to clinical trials: The promise of digital speech biomarkers in Parkinson's disease. Neurosci Biobehav Rev. 2024 Dec;167:105922. doi: 10.1016/j.neubiorev.2024.105922. Epub 2024 Oct 18. PMID: 39424108.
6.Schultz BG, Rojas S, St John M, Kefalianos E, Vogel AP. A Cross-sectional Study of Perceptual and Acoustic Voice Characteristics in Healthy Aging. J Voice. 2023 Nov;37(6):969.e23-969.e41. doi: 10.1016/j.jvoice.2021.06.007. Epub 2021 Jul 14. PMID: 34272139.
7.Helwan A, Azar D, Ma'aitah MKS. Conventional and deep learning methods in heart rate estimation from RGB face videos. Physiol Meas. 2024 Feb 9;45(2). doi: 10.1088/1361-6579/ad1458. PMID: 38081130.
8.Bauser M, et al. Voice Assessment and Vocal Biomarkers in Heart Failure: A Systematic Review. Circ Heart Fail. 2025 Aug;18(8):e012303. doi: 10.1161/CIRCHEARTFAILURE.124.012303. Epub 2025 Apr 24. PMID: 40270235.
9.Işık EE, Sapmaz Atalar M, Cangï ME, Develïoğlu ÖN, Esen Aydinli F. Aging and Voice: A Pilot Study Investigating Aerodynamic and Acoustic Measurements in Older Adults. J Voice. 2025 Sep 6:S0892-1997(25)00350-9. doi: 10.1016/j.jvoice.2025.08.027. PMID: 40915945.
Odiosoft Face Analysis — Longevity & Metabolic Assessment
Developed by Dr. Siyra Seren · Contactless imaging + voice biomarker · odiosoft.tech