
AI-Based Mobile Nail Health Platform
Contactless imaging, ABCDEF assessment and large language model (LLM) inference for nail disease screening, health scoring and cosmetic product allergen tracking.
Developed by Dr. Siyra Seren.
Disease ScreeningHealth ScoreProduct AllergenHuman-in-the-loop
Table of Contents
1What is AI Nail Analysis?
2Technology: Image Processing & LLM Inference
3Evaluated Parameters
4Clinical Value & Decision Support
5ESG & Sustainability
6Scientific References
Vision
A software-centric, hardware-independent dermatology intelligence platform that produces clinically meaningful nail assessment from consumer devices (smartphone, tablet).
Use Cases
In-clinic screening, teledermatology, cosmetic product safety and community-based nail disease early screening support.
1
Section 1
What is AI Nail Analysis?
& Cosmetic Allergen Tracking — NailGuard AI is an AI-powered mobile imaging support tool that non-invasively assesses nail health, disease screening and cosmetic product allergen tracking from a standard nail photograph. The system analyzes nail surface, color, thickness, shape and cuticle condition to screen for onychomycosis, psoriasis, melanonychia, onycholysis and ingrown nails.
Geometric and color changes in the nail alter light reflection/scattering characteristics. The AI quantifies these optical signatures through image processing and spectral analysis to produce a nail health score, brittleness/yellowing/thickness metrics and an ABCDEF melanonychia assessment.
Core Capabilities
- Disease screening: onychomycosis, psoriasis, melanonychia, onycholysis, ingrown nail
- ABCDEF criteria for melanonychia malignancy assessment
- Health score: brittleness, yellowing, thickness/hardness, shape, cuticle
- Product allergen: OCR ingredient reading + toxin/allergen flagging (PPD, formaldehyde, toluene, DBP)
Clinical Positioning
The system is a screening and decision-support tool; it does not replace a definitive medical diagnosis. AI models may err; outputs are produced to support a physician's clinical assessment. Final diagnosis and treatment decisions rest with the specialist physician.
2
Section 2
Technology: Image Processing & LLM Inference
The platform combines image processing and large language model (LLM)-based multimodal inference. From a standard RGB image, the nail region is segmented; surface, color and shape features are extracted and clinical inference is performed with a multimodal LLM.
Processing Flow
- Image capture & quality audit (brightness, contrast, sharpness, nail bounding box)
- Nail segmentation and zone-based feature extraction
- Multimodal LLM inference: disease score, health metrics, ABCDEF, allergen list, clinical commentary
- Summary metrics: health_score, confidence, risk_level, exposure_score
Software-Centric Architecture
Hardware-Independent
Runs only on the device's built-in camera; no extra medical hardware required.
Web-based (SaaS)
API-first architecture; integrates with EMR platforms, real-time remote monitoring.
AI Integration
Image processing + multimodal LLM for nail localization and disease mapping.
Telemedicine-Ready
Records stored as digital data; remote consultation and longitudinal tracking.
3
Section 3
Evaluated Parameters
The analysis provides multi-layer parameters across disease screening, health score and product allergen modules. Each parameter is reported as percentage (0-100), description, severity and risk level.
Disease Screening
Onychomycosis, psoriasis, melanonychia, onycholysis, ingrown nail
ABCDEF
Asymmetry, Border, Color, Diameter, Evolution, Family history
Health
Brittleness, yellowing, thickness/hardness, shape, cuticle
Risk Level
Low / Moderate / High risk categorization
Product Allergen
OCR ingredient reading + toxin/allergen flagging
Free-Claim
3/5/10-Free claim verification
Exposure
Barrier damage / exposure risk score (0-100)
Patient Match
Comparison of patient known allergens with product
Output Format
- Disease: primary_suspect, alternatives[], confidence, risk_level, abcdef_assessment
- Health: brittleness_index, yellowing_score, thickness_score, shape_assessment, cuticle_health
- Product: product_name, ingredients[], flagged_allergens[], exposure_score, free_claim_verified
- AI clinical commentary + personalized recommendations + printable full report (PDF)
4
Section 4
Clinical Value & Decision Support
The platform supports clinical workflows as a screening and pre-triage tool. Nail parameter mapping provides structured, reproducible and comparable data to the physician. Final diagnosis and treatment decisions always rest with the specialist physician.
Screening
Community/clinic-based non-invasive nail screening support.
Decision Support
Structured disease scores + ABCDEF + clinical AI commentary.
Tracking
Longitudinal trend and nail change monitoring.
Safety Architecture (Human-in-the-loop)
- AI output is not a diagnosis; it is information supporting the physician's assessment
- AI commentary does not contain prescription/treatment recommendations
- Per-patient data isolation (RLS) and KVKK/GDPR-aligned sensitive-data approach
Integration Scenarios
Teledermatology
Remote consultation, nail tracking and recording from mobile devices.
Product Safety
Cosmetic product ingredient allergen scanning and patient profile matching.
5
Section 5
ESG & Sustainability
The software-centric architecture aligns with European Union carbon-reduction and ESG (Environmental, Social, Governance) goals. Hardware independence brings medical consumable use close to zero and reduces the carbon footprint from patients' physical travel through telemedicine.
Zero Hardware
Eliminates carbon from production-to-disposal of dermatoscope/special cameras.
Zero Consumables
No single-use probes/apparatus; clinical waste near zero.
Digital Logistics
Web-based analysis removes the need for patient travel to the clinic.
Roadmap
Phase 1
Clinical deployment of nail disease screening and health score module.
Phase 2
Deep-learning-based automated melanonychia malignity scoring.
Phase 3
Personalized nail tracking and cosmetic safety suite.
6
Section 6
Scientific References
The following studies establish the clinical validity and methodological foundations of image-based AI assessment of nail diseases and nail condition. Our NailGuard AI platform draws inspiration from this literature but does not replace these methods.
1.Starace M, Alessandrini A, Piraccini BA. Dermoscopy of the Nail Unit. Dermatol Clin. 2021 Apr;39(2):293-304. doi: 10.1016/j.det.2020.12.008. Epub 2021 Feb 10.
2.Alessandrini A, Starace M, Piraccini BM. Dermoscopy in the Evaluation of Nail Disorders. Skin Appendage Disord. 2017 May;3(2):70-82. doi: 10.1159/000458728. Epub 2017 Mar 8.
3.Żychowska M, Tognetti L. Nail unit dermoscopy (onychoscopy) in the differential diagnosis of erythroderma. J Eur Acad Dermatol Venereol. 2023 May;37(5):e663-e665. doi: 10.1111/jdv.18861. Epub 2023 Jan 20.
4.Murali P, Mazumder DH. DermaScanAI an explainable hybrid deep learning framework for automated skin lesion classification using dual attention and metadata fusion. Sci Rep. 2026 Mar 26;16(1):15130. doi: 10.1038/s41598-026-46011-0.
5.Wu S. Hair and Nail Conditions: Alopecia Evaluation. FP Essent. 2022 Jun;517:11-16.
6.Lin K, Lipner SR. Mobile phone reminders for onychomycosis medication adherence. J Am Acad Dermatol. 2019 May;80(5):e105-e107. doi: 10.1016/j.jaad.2018.11.010. Epub 2018 Nov 14.
7.Mondillo G, Frattolillo V, Colosimo S, Perrotta A. Artificial Intelligence in Pediatric Nail Diseases: Limitations and Prospects. Balkan Med J. 2025 Jan 2;42(1):86. doi: 10.4274/balkanmedj.galenos.2024.2024-8-122.
8.Gaurav V, Grover C, Tyagi M, Saurabh S. Artificial Intelligence in Diagnosis and Management of Nail Disorders: A Narrative Review. Indian Dermatol Online J. 2024 Dec 11;16(1):40-49. doi: 10.4103/idoj.idoj_460_24. eCollection 2025 Jan-Feb.
9.Conway J, Bellet JS, Rubin AI, Lipner SR. Adult and Pediatric Nail Unit Melanoma: Epidemiology, Diagnosis, and Treatment. Cells. 2023 Mar 22;12(6):964. doi: 10.3390/cells12060964.
NailGuard AI — Nail Health & Disease Screening Platform
Developed by Dr. Siyra Seren · Contactless imaging · AI decision support · odiosoft.tech